The ketogenic diet in childhood epilepsy: where are we now? First Name. Reply: Most days he eats during a three-hour window, usually a small afternoon snack like beef jerky and then his evening meal. You might have also considered trying alternative therapies, like diet changes. Symptoms of bipolar illness improved in Asa, Sharon and Allison. Discussion Main findings This observational analytic study of bipolar disorder online forums provides some preliminary support for the hypothesis that a ketogenic diet can have beneficial effects on mood stabilisation that can be long lasting. In the study, 10 women with schizophrenia followed a ketogenic diet for two weeks, along with their standard treatment of medication and ECT electroconvulsive therapy, which led to a significant decrease in symptoms.
For more than 50 years, researchers have examined the effect of a ketogenic diet on patients with behavioral health disorders. The ketogenic diet is an established option for treatment-resistant epilepsy, as evidenced by a range of studies, including controlled trials. Bipolar disorder: One case study reported a reduction in symptomatology whereas a second case study reported no improvement. Depression: The ketogenic diet significantly reduced depression-like behaviors in rat and mice models in 2 controlled studies. Schizophrenia: An open-label study in female patients found reduced symptoms after 2 weeks of the ketogenic diet whereas a single case study reported no improvement; however, 3 weeks of the ketogenic diet in a mouse study normalized pathological behaviors. The Bostock review did not include studies regarding how the ketogenic diet affects dementia and Alzheimer disease. A 6-week study of a low-carbohydrate diet in persons with mild cognitive impairment saw improvement in verbal memory, with greater benefits for persons who achieved higher ketone levels. Dr Ede agreed that the research is not there — yet. We clearly need high-quality human studies exploring the effects of ketogenic diets on mental health disorders, as many clinicians and patients will be afraid to utilize this diet without stronger evidence.
The exact causes of bipolar disorder formerly known as manic depressive illness are unknown. Current treatments are mainly medications, which supposedly correct these imbalances. When medications fail to work, treatments can also include transcranial magnetic stimulation TMS and electroconvulsive therapy ECT. Many treatments that are approved for the treatment of epilepsy also work for bipolar disorder and other psychiatric disorders, including medications like Depakote valproic acid, Tegretol carbamazepine, and Lamictal lamotrigine. Other anticonvulsant medications are used off label very commonly in the treatment of bipolar disorder. Given the overlap in effective treatments, it is not unreasonable to question if the evidence-based ketogenic diet might play a role in the treatment of bipolar disorder, at least for some people.